Method for preparing 7.beta.-hydroxy-4-pregnene-3,20-dione deriv

Details Method for preparing 7.beta.-hydroxy-4-pregnene-3,20-dione deriv Method for preparing 7.beta.-hydroxy-4-pregnene-3,20-dione deriv

1989-11-15

1992-11-17

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

435 52, 435 56, 435911, 435254, C12P 3300, C12P 3312, C12P 3306, C12N 114

Patent

active

051643022

ABSTRACT:
Novel 7.beta.-hydroxy-4-pregnene-3,20-dione derivatives are disclosed.
The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themselves have also cell differentiation activity for M1 cells.

REFERENCES:
patent: 2879280 (1959-03-01), Fried
patent: 2962512 (1960-11-01), Bernstein
patent: 3031477 (1962-04-01), Thoma
patent: 3125495 (1964-03-01), Laskin
ATCC Catalogue of Fungi, 1987, pp. 4-6.
ATCC Catalogue of Fungi, 1981, pp. 6 and 86.
Chem. Abstracts, vol. 55, No. 17, Aug. 21, 1961; Tsuda et al; "Microbiological hydroxylation of steroids". X. 7.beta.,15.beta.-dihydroxypregn-4-ene-3,20-dione.
Journal of Chemical Ecology, vol. 13, No. 1, Jan. 1987, pp. 35-38; Meinwald et al, "Defensive steroids from carrion beetle."

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