Method for preparing 1,3-disubstituted pyrrolidine compounds

Details Method for preparing 1,3-disubstituted pyrrolidine compounds Method for preparing 1,3-disubstituted pyrrolidine compounds

2007-09-07

2011-11-15

Chu, Yong (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S422000

Reexamination Certificate

active

08058454

ABSTRACT:
A process for preparing substituted pyrrolidine compounds, including (5)-2-{1-[2-(2,3-dihydrobenzofuran-5-yl)ethyl]-3-pyrrolidinyl}-2,2-diphenylacetamide hydrobromide, commonly known in the art as darifenacin, comprising reacting a pyrrolidine compound with a benzofuran derivative in the presence of a phase-transfer catalyst.

REFERENCES:
patent: 5096890 (1992-03-01), Cross et al.
patent: 0 388 054 (1990-09-01), None
patent: WO 2007076157 (2007-07-01), None

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