Method for preparing 1,2-dithiins and precursors of 1,2-dithiins

Details Method for preparing 1,2-dithiins and precursors of 1,2-dithiins Method for preparing 1,2-dithiins and precursors of 1,2-dithiins

1994-10-05

1995-12-26

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

568 39, 568 41, 568 56, 568 57, 558252, C07F 722, C07C32718, C07C32305, C07C32322

Patent

active

054789591

ABSTRACT:
A method for preparing 1,4-(Z,Z)-disubstituted-1,4-disulfurated-1,3-butadienes is disclosed. The butadienes can be further elaborated to provide 3,6-unsymmetrically-substituted-1,2-dithiins. Also disclosed are butadienes prepared by the method of the invention. These butadienes are useful as intermediates in the synthesis of antibiotic 1,2-dithiins.

REFERENCES:
patent: 2061019 (1936-11-01), Carter et al.
patent: 3096375 (1963-07-01), Campbell et al.
patent: 5202348 (1993-04-01), Towers et al.
Schroth et al., "1,2-Dithiins, a New Type of Heterocycle", vol. 6, No. 8 pp. 649-722, Aug. 1967, Angew. Chem, Int. Ed.
Towers et al. "Antibiotic Properties of Thiaurbrine A, a Naturally . . . " Planta Medica, 225-229 (1985).
Eisner et al. "Recent Developments in the Chemistry of o-and m-Dithins" Int. J. Sulfur Chem., B, 7, 101-107 (1972).
Hartke et al. "Eigenschaften und Reaktionen der Thiobernstein-und Thioglutarsaureester" Liebigs Ann. Chem., 933-941 (1988).
Koreeda et al. "The Chemistry of 1,2-Dithiins: Synthesis of 1,2-Dithin and 3,6-Disubstituted . . . " Synlett, 201-203 (1994).
Zhang et al. "Palladium-and Molybdenum-Catalyzed Hydrostannation of Alkynes. A Novel Access . . . " J. Org. Chem., 55: 1857-1867 (1989).
Margiotis et al. "A Novel Approach to the Synthesis of Enediynes" Tetrahedron Letters 32, 6085-6088 (1991).
Magriotis et al. "A Highly Selective Synthesis of Versatile (E)-1-Phenylthio Vinystannanes" Tetrahedron Letters 32, 5047-5050 (1991).

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