Method for preparation of F-18 containing organofluoro...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S122000, C546S132000, C548S327500, C552S537000, C558S427000, C570S134000

Reexamination Certificate

active

07847092

ABSTRACT:
The present invention relates to a method for preparation of organofluoro compounds containing radioactive isotope fluorine-18. More particularly, the present invention relates to a method for preparation of primary or secondary organofluoro compound by reacting fluorine salt containing radioactive isotope fluorine-18 with primary or secondary alkyl halide or primary or secondary alkyl sulfonate in the presence of alcohol of Chemical Formula 1 as a solvent to obtain high yield of organofluoro compound. Synthesis reaction according to the present invention may be carried out under mild condition to give high yield of the organofluoro compounds and the reaction time is decreased, and thereby is suitable for the mass production of the organofluoro compounds.

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Free Dictionary “alkyl”; also available at http://www.freedictionary.org/?Query=alkyl; last viewed Jun. 24, 2010.
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