Method for preparation of azetidinone-1-oxoacetate by oxidation

Details Method for preparation of azetidinone-1-oxoacetate by oxidation Method for preparation of azetidinone-1-oxoacetate by oxidation

1987-03-20

1988-06-14

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07F 718, C07D40512, C07D40914, C07B 4106

Patent

active

047512970

ABSTRACT:
A process for production of a 2-azetidinone-1-oxoacetate of the formula ##STR1## useful as an intermediate for preparation of 2-SR.sup.2 -substituted-2-penem-3-carboxylate andtibacterial agents;
R is a conventional hydroxy protecting group, R.sup.1 is certain carboxy protecting groups and ##STR2## and m and n are each 0, 1 or 2; which comprises contacting a corresponding (2-oxo-1-axetidinyl)-N-2-hydroxyacetate ester of the formula ##STR3## with manganese dioxide.

REFERENCES:
patent: 4155915 (1979-05-01), Menard et al.
patent: 4619924 (1986-10-01), Hamanaka
Sankyo, Chem Abs 98, 143190w (1982).
C. R. Johnson et al., J. American Chem. Soc., 91, 682-687 (1969).
Durst, Advances in Org. Chem., 6, 356-365 (1969).
A. J. Fatiadi, Synthesis, 65-104; 133-167 (1976).

Affiliated with

Also associated with

Rating

Method for preparation of azetidinone-1-oxoacetate by oxidation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparation of azetidinone-1-oxoacetate by oxidation , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparation of azetidinone-1-oxoacetate by oxidation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-505758