Method for predicting tumor recurrence

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007210

Reexamination Certificate

active

10668057

ABSTRACT:
The present invention provides methods and kits for predicting recurrence of tumor or cancer in a mammal by calculating the ratio of the amount of Survivin to the amount of pro-apoptosis factor (PAF) in a physiological sample.

REFERENCES:
patent: 6001962 (1999-12-01), Ramer et al.
patent: 6077709 (2000-06-01), Bennett et al.
patent: 6103237 (2000-08-01), Saedi et al.
patent: 6656684 (2003-12-01), Sandler
Krieg A et al. British Journal of Cancer 86: 737-743, 2002.
Mahotka C et al. Cancer Research 59: 6097-6102, 1999.
Fu L et al. EMBO Journal 15(16): 4392-4401, 1996.
Powell H et al. Pharmacogenetics 8(5): 411-421, 1998 (Abstract only enclosed).
Vallejo CG et al. Biochimie 82(12): 1129-1133, 2000 (Abstract only enclosed).
Jang A et al. Clin Exp Metastasis 15(5): 469-483, 1997 (Abstract only enclosed).
Altieri DC Trends in Molecular Medicine 7(12): 542-547, 2001.
Lu C et al. Cancer Research 58: 1808-1812, 1998.
LaCasse EC et al. Oncogene 17, 3247-3259, 1998.
Adida C et al. The Lancet 351: 882-883, 1998.
Tamm I et al. Cancer Research 5315-5320, 1998.
Adida, C. , et al., “Anti-apoptosis gene, survivin, and prognosis of neuroblastoma”,The Lancet, 351, (1998),pp. 882-883.
Ambrosini, G. , et al., “A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma”,Nature Medicine, 3 (8), (1997),pp. 917-921.
Ashkenazi, A. , et al., “Death Receptors: Signaling and Modulation”,Science, 281 (5381), (1998),pp. 1305-1308.
Breslow, N. , et al., “Epidemiology of Wilms Tumor”,Medical and Pediatric Oncology, 21 (3), (1993),pp. 172-181.
Brodeur, G. M., et al., “Neuroblastoma”,In: Principles and Practice of Pediatric Oncology, Chapter 29, (1997),pp. 761-797.
Deveraux, Quinn L., et al., “X-Linked IAP is a Direct Inhibitor of Cell-Death Proteases”,Nature, 388 (6639), (1997),pp. 300-304.
Donaldson, S. A., et al., “Expression of Fas/APO-1 by different clinical stages of human neuroblastoma”,Proceedings of the American Association for Cancer Research, 40, Abstract No. 1141,(Mar. 1999),p. 171.
Li, F. , et al., “Control of apoptosis and mitotic spindle checkpoint by survivin”,Nature, 396, (1998),pp. 580-584.
Li, F. , et al., “Pleiptropic cell-devision defects and apoptosis induced by interference with survivin function”,Nature Cell Biology, 1 (8), (1999),pp. 461-466.
Liston, P. , et al., “Supression of apoptosis in mammalian cells by NAIP and a related family of IAP genes”,Nature, 379, (1996),pp. 349-353.
Lowry, O. H., et al., “Protein Measurements With The Folin Phenol Reagent”,The Journal of Biological Chemistry, 193, (1951),pp. 265-275.
Lu, C. , et al., “Expression of A Novel Antiapoptosis Gene, Survivin, Correlated with Tumor Cell Apoptosis and p53 Accumulation in Gastric Carcinomas”,Cancer Research, 58 (9), (1998),pp. 1808-1812.
Miller, L. J., et al., “Apoptosis”,Science, 281 (5381), (1998),p. 1301.
Sandler, A. , et al., “Survivin in Apoptosis and Solid Tumors of Childhood”.Surgical Forum, 85th Annual Clinical Congress, vol. L, (1999),pp. 571-572.
Sarela, et al., “Expression of the Antiapoptosis Gene, Survivin, Predicts Death from Recurrent Colorectal Carcinoma”,Gut, 46, (May 2000),645-650.
Swana, H. S., et al., “Tumor Content of the Antiapoptosis Molecule Survivin and Recurrence of Bladder Cancer”,The New England Journal of Medicine, 341 (6), (1999),pp. 452-453.
Takamizawa, S. , et al., “Differential Apoptosis Gene Expression in Pediatric Tumors of the Kidney”,Journal of Pediatric Surgery, 35 (2), (Feb. 2000),pp. 390-395.
Tamm, I. , et al., “IAP-Family Protein Survivin Inhibits Caspase Activity and Apoptosis Induced by Fas (CD95), Bax, Caspases, and Anticancer Drugs”,Cancer Research, 58 (23), (1998),pp. 5315-5320.
Thompson, C. B., “Apoptosis in the Pathogenesis and Treatment of Disease”,Science, 267, (1995),pp. 1456-1462.
Azuhata et al., “The inhibitor of apoptosis protein survivin is associated with high-risk behavior of neuroblastoma”,J. Pediatr Surg., 36 (12), 1785-1791 (2001).
Sandler et al., “The survivin:fas ratio is predictive of recurrent disease in neuroblastoma”,J. Pediatr Surg., 37(3), 507-511 (2002).
Takamizawa et al., “The survivin:fas ratio in pediatric renal tumors”,J Pediatr Surg., 36(1), 37-42 (2001).

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