Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Reexamination Certificate
2011-08-16
2011-08-16
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
C435S028000, C514S263360, C514S419000
Reexamination Certificate
active
07998698
ABSTRACT:
Provided is a method for determining whether an individual is likely to be susceptible to radiation pneumonitis from radiation therapy and for developing a treatment based on the determination of susceptibility. The method involves measuring SOD and GPX activity levels. A high SOD or low GPX activity, or a combination thereof, is indicative that the individual is likely to be susceptible to radiation pneumonitis.
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Yang, et al.; “High Superoxide Dismutase (SOD) and Low Glutathione Peroxidase (GPX) Activities in Red Blood Cells (RBCs) Predict Susceptibility of Lung Cancer Patients to Radiation Pneumonitis”; International Journal of Radiation Oncology Biology Physics, Nov. 1, 2006 (available online Oct. 12, 2006), vol. 66, Issue 3, Supp. 1; pp. S463-S464; Abstract No. 2458.
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Park Young-Mee
Ramnath Nithya
Yang Gary Y.
Gitomer Ralph
Health Research , Inc.
Hodgson & Russ LLP
Yamasaki Robert
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