Method for potentiation of a therapeutic agent

Details Method for potentiation of a therapeutic agent Method for potentiation of a therapeutic agent

1990-11-19

1992-10-13

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 4, 514825, 514885, 514886, 514893, 514966, 514967, A61K 3726

Patent

active

051550962

ABSTRACT:
The invention relates to a method for potentiation of a therapeutic agent, the method comprising the steps of administering an effective dose of insulin to induce to hypoglycemia; administering a pre-determined dose of a therapeutic agent; and administering a pre-determined dose of glucose sufficient to substantially neutralize the hypoglycemia. As an adjuvant system, the instant invention constitutes the combination of a quantity of insulin in the range of one to four units per 10 kilograms of body weight; a pre-determined quantity of the therapeutic agent; and glucose in the form of a hypertonic solution between about 5% and about 50% glucose, the volume of the solution being in the range of about 10 cubic centimeters to about 100 cubic centimeters. The inventive method is known as Insulin Potentiation Therapy (IPT).

REFERENCES:
patent: 4971951 (1990-11-01), Garcia y Bellon et al.

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