Method for performing spacially coordinated high speed...

Radiant energy – Luminophor irradiation

Reexamination Certificate

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Details

C250S459100, C356S317000, C356S318000

Reexamination Certificate

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11184721

ABSTRACT:
An optical imager, such as a microscope for performing multiple frequency fluorometric measurements comprising a light source, such as a laser source is disclosed. The system is used to excite a sample into the fluorescent state. Light from the excited sample is collected by a microscope. The microscope utilizes conventional confocal optics optimized to have a very narrow depth of field, thus limiting the information collected to a thin planar region. Measurements are taken over the fluorescence lifetime of the sample simultaneously from the excitation source and from the excited sample. Information is taken in a matrix and comparison of the image matrix and the standard during simultaneous measurements yields output information.

REFERENCES:
patent: 5865754 (1999-02-01), Sevick-Muraca et al.
patent: 6496267 (2002-12-01), Takaoka
patent: 6741346 (2004-05-01), Gerstner et al.
patent: 2002/0072677 (2002-06-01), Sevick-Muraca et al.
patent: 2004/0156053 (2004-08-01), Wolleschensky et al.

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