Method for performing a solid-phase extraction under pressurized

Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...

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210674, 210679, B01D 1500

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active

053912985

ABSTRACT:
A method of performing a solid phase extraction on an aqueous fluid using a hydrophobic, solid-phase extraction medium (40), which method comprises:
(a) placing (10) a hydrophobic, solid-phase extraction medium (40) inside of a pressurizable housing (18) having an inlet (25) and an outlet (32), the hydrophobic, solid-phase extraction medium (40) being positioned in the pressurizable housing (18) such that a liquid moving from the inlet (25) to the outlet (32) passes through the solid-phase extraction medium (40);
(b) priming (12) the hydrophobic, solid-phase extraction medium (40) with a water-miscible organic liquid by passing the water-miscible organic liquid from the inlet (25) to the outlet (32) under positive pressure; and
(c) passing (14) an aqueous liquid from the inlet (25) to the outlet (32) under positive pressure;
wherein the water-miscible organic liquid and aqueous liquid are passed from the inlet (25) to the outlet (32) such that the solid-phase extraction medium (40) is completely and continuously immersed in liquid in the pressurizable housing (18) during steps (b) and (c).

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