Radiant energy – Ionic separation or analysis – Cyclically varying ion selecting field means
Patent
1999-05-17
2000-11-14
Nguyen, Kiet T.
Radiant energy
Ionic separation or analysis
Cyclically varying ion selecting field means
250282, H01J 4942
Patent
active
061473480
ABSTRACT:
The subject invention pertains to a scan function which will allow parent and neutral loss scans, with a reduced number of false positives, greater detection efficiency, shortened time periods, and enhanced mass resolution, to be performed on the quadrupole ion trap mass spectrometer. In a specific embodiment, the subject invention involves first trapping ions of interest and obtaining a mass spectrum of the m/z range of interest. The (m/z)'s which are present and meet certain predetermined criteria can then be selected and stored. Ions are again trapped in the ion trap and then all ions with (m/z)'s below that of the first ion of interest are ejected. The first ion of interest is resonantly excited to cause CID and the presence of a particular daughter ion is then determined using a standard mass-selective instability scan over a narrow m/z range with resonant ejection at a predetermined ejection q.sub.z. The ion trap is then cleared of all ions with (m/z)'s below that of the next ion of interest and the process is repeated.
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Quarmby Scott T.
Yost Richard A.
Nguyen Kiet T.
University of Florida
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