Method for palliation of pain in human bone cancer using therape

Details Method for palliation of pain in human bone cancer using therape Method for palliation of pain in human bone cancer using therape

1996-11-04

1998-12-29

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

534 10, 600 1, 600 3, A61K 5104, C07F 500, A61N 500

Patent

active

058536957

ABSTRACT:
The invention provides a method for the palliation of bone pain due to cancer by the administration of a unique dosage of a tin-117m (Sn-117m) stannic chelate complex in a pharmaceutically acceptable composition. In addition, the invention provides a method for simultaneous palliation of bone pain and radiotherapy in cancer patients using compositions containing Sn-117m chelates. The invention also provides a method for palliating bone pain in cancer patients using Sn-117m-containing compositions and monitoring patient status by imaging the distribution of the Sn-117m in the patients. Also provided are pharmaceutically acceptable compositions containing Sn-117m chelate complexes for the palliation of bone pain in cancer patients.

REFERENCES:
patent: 4533541 (1985-08-01), Srivastava et al.
Harold L. Atkins et al., "Biodistribution of Sn-117m(4+) DTPA for Palliative Therapy of Painful Osseous Metastases," Radiology, 186, 279-283 Jan. 1993.

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