Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1993-06-14
1995-06-27
Robinson, Douglas W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 281, 536 284, 536 285, 536 2851, 536 2852, 536 2853, 536 2854, C07H 1900
Patent
active
054281490
ABSTRACT:
This invention discloses an improved method for the preparation of a superior palladim catalyst that is capable of coupling vinyl and aryl stannanes to 2'-deoxy-5-iodouridine.
REFERENCES:
patent: Re34069 (1992-09-01), Koster et al.
patent: 4415732 (1983-11-01), Caruthers et al.
patent: 4725677 (1988-02-01), Koster
patent: 4904582 (1990-02-01), Tullis
patent: 4923901 (1990-05-01), Koester et al.
patent: 4948882 (1990-08-01), Ruth
patent: 5023243 (1991-06-01), Tullis
patent: 5047519 (1991-09-01), Hobbs, Jr. et al.
patent: 5118672 (1992-06-01), Schinazi et al.
patent: 5118800 (1992-06-01), Smith et al.
patent: 5118802 (1992-06-01), Smith et al.
patent: 5134066 (1992-07-01), Rogers et al.
patent: 5138045 (1992-08-01), Cook et al.
Crisp and Flynn (1990) Tetrahedron Letters 31:1347 "Palladium-catalyzed coupling of uridine triflate with organostannanes".
Yamamoto et al (1989) J. Org. Chem. 54:4734 "New method for the synthesis of boron-10 containing nucleoside . . . ".
Crisp (1989) Synthetic Communications 19:2117 "Synthesis of 5-alkenyl-2'-deosyuridines via organostannenes."
Bigge and Mertes (1981) J. Org. Chem. 46:1994 "A palladiuum-catalyzed coupling reaction and a photolytic . . . ".
Hacksell and Daves (1983) J. Org. Chem. 48:2870 "Stereo-controlled palladium (II)-mediated coupling of furanoid . . . ".
Gergstrom and Ruth (1976) J. Am. Chem. Soc. 98:1587 "Synthesis of C-5 sustituted pyrimidine nucleosides via organopalladium . . . ".
Bergstrom et al. (1982) J. Org. Chem. 47:2174 "Pyrido (2,3-d) pyrimidine nucleoside antibiotic . . . ".
Ruth and Bergstrom (1978) J. Org. Chem. 43:2870 "C-5 substituted pyrimidine nucleosides . . . ".
Bergstrom et al. (1981) J. Org. Chem. 46:1423 "Pyrrolo (2,3-d) pyrimidine nucleoside antibiotic analogues."
Bergstrom et al. (1981) J. Org. Chem. 46:1432 "C-5-substituted pyrimidine nucleosides."
Stille (1986) Angew. Chem. Int. Ed. Engl. 25:508, "The palladium-catalyzed cross-coupling . . . ".
Arai and Daves (1970) J. Am. Chem. Soc. 100:287 "Regiospecific reaction of enol, ethers . . . ".
Still and Groh (1987) J. Am. Chem. Soc. 109:813 "Stereo-specific cross-coupling of vinyl halides . . . ".
Scott and Stille (1986) J. Am. Chem. Soc. 108:3033 "Palladium-catalyzed and coupling of vinyl triflates . . . ".
Paillargeon and Stille (1983) J. Am. Chem. Soc. 105:7175 "Direct conversion of organic halides to aldehydes . . . ".
Dreyer and Dervan (1985) Proc. Natl. Acad. Sci. USA 82:968 "Sequence-specific cleavage of single-stranded DNA . . . ".
Brown and Cooley (1990) Organometallics 9:353 "Mapping the reaction pathway in palladium-catalyzed . . . ".
Graaf et al. (1990) Organometallics 9:1479 "Cross-coupling versus homocoupling . . . ".
Albano and Castellari (1990) Organometallics 9:1269 "Synthesis and characterization of five-coordinate olefin . . . ".
Chemical Abstract: vol. 115: 92415h, Sentemov et al.
Robinson Douglas W.
Washington State University Research Foundation
Wilson James Oliver
LandOfFree
Method for palladium catalyzed carbon-carbon coulping and produc does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for palladium catalyzed carbon-carbon coulping and produc, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for palladium catalyzed carbon-carbon coulping and produc will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-288561