Method for optimizing reagents for agglutination reactions

Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...

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23230B, 424 8, 424 11, 424 13, 435 7, G01N 3100, G01N 3316

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active

041645588

ABSTRACT:
A method and compositions are provided to effect optimization of methods for determining concentrations of antibodies or antigens. Particles coated with an antigen or an antibody are suspended in an aqueous medium where pH and ionic strength are controlled so that the coulomb effect and the van der Waals forces on and exerted by the particles are balanced.

REFERENCES:
von Schulthess et al., Immunochem., vol. 13, No. 12, 1976, pp. 955-962 (published Jan. 12, 1977).
Oreskes, J. Immunology, vol. 86, 1961, pp. 338-343.
Van Oss, Res-J. Soc. Retic. Soc., vol. 3, 1966, pp. 29-40.
Sobers, Bayou Tech., La. State Soc. Med. Tech., vol. XVII, May, 1973, pp. 18-20, 22.

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