Method for optical resolution of DL-lysine compounds

Details Method for optical resolution of DL-lysine compounds Method for optical resolution of DL-lysine compounds

1977-09-01

1978-08-22

Tanenholtz, Alvin

Textiles: fiber preparation

195 3R, 195 29, 195 30, 195DIG11, C07B 1902

Patent

active

041087232

ABSTRACT:
A method for optical resolution of DL-lysine alkyl ester or acid-addition salts thereof by contacting an aqueous solution of the ester or salts thereof with a non-specific protease obtained by culturing bacteria belonging to the genus Streptomyces, e.g. St. griseus, at weakly acidic pH and a temperature not exceeding 60.degree. C until 60 - 90% by weight of L-lysine ester or acid-addition salts thereof takes part in a reaction, and recovering L-lysine or acid-addition salts thereof thus produced by a conventional manner. The protease may be immobilized on an insoluble carrier in advance.

REFERENCES:
patent: 3816254 (1974-06-01), Chibata et al.
patent: 3963573 (1976-06-01), Stauffer

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