Method for optical measurement of bilirubin and reagent therefor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 4, 435189, 435191, 436 12, 436 97, 436100, 436101, C12Q 126, G01N 3300

Patent

active

052623041

ABSTRACT:
A method for optical measurement of bilirubin which comprises reacting a bilirubin-containing sample with a zinc compound, a coloring agent and bilirubin oxidase in a buffer, wherein a stable green pigment having a large molecular extinction coefficient is formed by the action of the zinc compound and thereby bilirubin in the sample can be measured specifically, and a reagent useful therefor. Said method and the reagent are useful for clinical test of total bilirubin and direct bilirubin in serum.

REFERENCES:
patent: 4211844 (1980-07-01), Wu
patent: 4571383 (1986-02-01), Takayama et al.
patent: 4600689 (1986-07-01), Matsui et al.
patent: 4895799 (1990-01-01), Kruse-Muller et al.
Simunek et al., Chemical Abstracts, vol. 97, Ref. No. 35567v, 1982.
Doumas et al., Clinical Chemistry, vol. 31, No. 11, pp. 1779-1789, 1985.
Johnson et al, Clinical Chemistry, vol. 23, No. 7, pp. 1321-1327, 1977.
Worth et al, The Journal of Laboratory and Clinical Medicine, vol. 70, No. 2, pp. 352-354, 1967.
Corns et al., Chemical Abstracts, vol. 108, Ref. No. 18708v, 1988.
Japanese Patent First Publication No. 112068/1987, with English language summary.
Nature, vol. 195, Aug. 4, 1962, p. 490, "Quantitative Determination of Bilrubin and other Tetrapyrrols".
Patent Abstracts of Japan, vol. 8, No. 251, Nov. 16, 1984, 59-130198, Jul. 26, 1984.
Patent Abstracts of Japan, vol. 11, No. 328, Oct. 27, 1987, 62-112068, May 23, 1987.
Worth et al., "Basic zinc test for urine bilirubin", The Journal of Laboratory and Clinical Medicine, vol. 70, No. 2, Aug. 1967, pp. 352-354.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for optical measurement of bilirubin and reagent therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for optical measurement of bilirubin and reagent therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for optical measurement of bilirubin and reagent therefor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-21686

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.