Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Patent
1990-12-18
1993-11-16
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
435 4, 435189, 435191, 436 12, 436 97, 436100, 436101, C12Q 126, G01N 3300
Patent
active
052623041
ABSTRACT:
A method for optical measurement of bilirubin which comprises reacting a bilirubin-containing sample with a zinc compound, a coloring agent and bilirubin oxidase in a buffer, wherein a stable green pigment having a large molecular extinction coefficient is formed by the action of the zinc compound and thereby bilirubin in the sample can be measured specifically, and a reagent useful therefor. Said method and the reagent are useful for clinical test of total bilirubin and direct bilirubin in serum.
REFERENCES:
patent: 4211844 (1980-07-01), Wu
patent: 4571383 (1986-02-01), Takayama et al.
patent: 4600689 (1986-07-01), Matsui et al.
patent: 4895799 (1990-01-01), Kruse-Muller et al.
Simunek et al., Chemical Abstracts, vol. 97, Ref. No. 35567v, 1982.
Doumas et al., Clinical Chemistry, vol. 31, No. 11, pp. 1779-1789, 1985.
Johnson et al, Clinical Chemistry, vol. 23, No. 7, pp. 1321-1327, 1977.
Worth et al, The Journal of Laboratory and Clinical Medicine, vol. 70, No. 2, pp. 352-354, 1967.
Corns et al., Chemical Abstracts, vol. 108, Ref. No. 18708v, 1988.
Japanese Patent First Publication No. 112068/1987, with English language summary.
Nature, vol. 195, Aug. 4, 1962, p. 490, "Quantitative Determination of Bilrubin and other Tetrapyrrols".
Patent Abstracts of Japan, vol. 8, No. 251, Nov. 16, 1984, 59-130198, Jul. 26, 1984.
Patent Abstracts of Japan, vol. 11, No. 328, Oct. 27, 1987, 62-112068, May 23, 1987.
Worth et al., "Basic zinc test for urine bilirubin", The Journal of Laboratory and Clinical Medicine, vol. 70, No. 2, Aug. 1967, pp. 352-354.
Mohamed Abdel A.
Nippon Shoji Kabushiki Kaisha
Wityshyn Michael G.
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