Method for obtaining uniform fractions of hyperpolymeric hemoglo

Details Method for obtaining uniform fractions of hyperpolymeric hemoglo Method for obtaining uniform fractions of hyperpolymeric hemoglo

1998-04-08

1999-11-30

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530402, 530412, 530418, 530427, 530815, 514 6, 514832, A61K 3514, A61K 3816

Patent

active

059945095

ABSTRACT:
A process for preparing solutions of hemoglobin hyperpolymers by fractionating hemoglobin hyperpolymers having a nonuniform molecular weight distribution according to molecular weight using a polyhydroxy compound to precipitate different fractions of hemoglobin hyperpolymers, wherein each fraction has a different but more uniform molecular weight distribution as compared to the starting hemoglobin hyperpolymers. Preferably, the polyhydroxy compound is a polyalcohol, especially polyethylene glycol.

REFERENCES:
patent: 4001401 (1977-01-01), Bonsen et al.
patent: 4179337 (1979-12-01), Davis et al.
patent: 5252714 (1993-10-01), Harris et al.
patent: 5312808 (1994-05-01), Shorr et al.
patent: 5386014 (1995-01-01), Nho et al.
patent: 5814601 (1998-09-01), Winslow et al.
Potzschke et al., Advances in Expermental Medicine and Biology, vol. 345, pp. 205-213, 1994.
Artificial Cell Blood substitutes and Immobilization Biotechnology 22 (3). 1994, 641-649, Kan, P. et al, "Application of aqueous . . . blood".
Biopolymers 23 (12). 1984, 2761-2779, Haire, R.N. et al., "The Precipitation . . . System".

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