Method for obtaining information and device therefor

Details Method for obtaining information and device therefor Method for obtaining information and device therefor

2008-01-22

2010-12-14

Berman, Jack I (Department: 2881)

Radiant energy

Ionic separation or analysis

With sample supply means

C250S287000

Reexamination Certificate

active

07851749

ABSTRACT:
A method for obtaining information on a mass of an object by time-of-flight mass spectrometry. This method includes placing colloidal metal particles for promoting ionization of the object inside the object at a depth ranging from 0.1 nm to 100 nm in opposition to a primary beam for the ionization; irradiating the object with the primary beam selected from the group of ions, neutral particles, and electrons, which can be focused, pulsed, and are capable of scanning, and laser beams, which can be focused, pulsed, and are capable of scanning to ionize a constituent of the object and to allow the ionized constituent to fly out of the object; and obtaining information on the mass of the flying constituent of the object by time-of-flight mass spectrometry.

REFERENCES:
patent: 4920264 (1990-04-01), Becker
patent: 6110343 (2000-08-01), Ramsey et al.
patent: 6707038 (2004-03-01), Ellson et al.
patent: 7701138 (2010-04-01), Hashimoto et al.
patent: 2005/0035284 (2005-02-01), Schultz et al.
patent: 2005/0230615 (2005-10-01), Furutani et al.
patent: 2006/0118711 (2006-06-01), Murayama et al.
patent: 2006/0183235 (2006-08-01), Hashimoto et al.
patent: 2006/0202130 (2006-09-01), Kollmer et al.
patent: 2006/0211106 (2006-09-01), Komatsu et al.
patent: 2007/0158549 (2007-07-01), Naya et al.
patent: 2006-10658 (2006-01-01), None
patent: 2005/003715 (2005-01-01), None
DiCola et al. “Persistence Length of Titin from Rabbit Skeletal Muscles measured with Scattering and Microrheology Techniques,” BioPhysical Journal, vol. 88, Jun. 2005, 4095-4106.
Kuang Jen Wu et al., “Matrix-Enhanced Secondary Ion Mass Spectrometry: A Method for Molecular Analysis of Solid Surfaces,” 68(5) Anal. Chem. 873-82 (Mar. 1996).
Anna M. Belu et al., “Enhanced TOF-SIMS Imaging of a Micropatterned Protein by Stable Isotope Protein Labeling,” 73(2) Anal. Chem. 143-50 (with supporting information, pp. 1-4) (Jan. 2001).
David S. Mantus et al., “Static Secondary Ion Mass Spectrometry of Adsorbed Proteins,” 65(10) Anal. Chem. 1431-38 (May 1993).
Matthew S. Wagner et al., “Limits of detection for time of flight secondary ion mass spectrometry (ToF-SIMS) and X-ray photoelectron spectroscopy (XPS): detection of low amounts of adsorbed protein,” 13(4) J. Biomater. Sci. Polymer Edn 407-28 (2002).
Young-Pil Kim et al., “Gold Nanoparticle-Enhanced Secondary Ion Mass Spectrometry Imaging of Peptides on Self-Assembled Monolayers,” 78(6) Anal. Chem. 1913-20 (2006).
Isobe Toshiaki et al., Eds., Experimental Medical Science, Additional Volume, Proteome Analysis, 2000, Yodosha Co., pp. 22-24 & 129-136.

Affiliated with

Also associated with

Rating

Method for obtaining information and device therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for obtaining information and device therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for obtaining information and device therefor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4230104