Method for obtaining estrogens from mare's urine

Details Method for obtaining estrogens from mare's urine Method for obtaining estrogens from mare's urine

2004-06-01

2008-10-21

Badio, Barbara P (Department: 1612)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

active

07439235

ABSTRACT:
A method for obtaining an extract from a natural mixture of conjugated estrogens from the urine of pregnant mares (PMU) by solid-phase extraction on semipolar adsorption resins in which the resulting extract meets the pharmaceutical specifications for conjugated estrogens and the content of free estrogens is minimized even if old pregnant mares' urine and/or pregnant mares' urine which has been stored or transported at elevated temperatures is used.

REFERENCES:
patent: 3769401 (1973-10-01), Thompson
patent: 5723454 (1998-03-01), Ban et al.
patent: 7081451 (2006-07-01), Ahnsorge et al.
patent: 2003/0105344 (2003-06-01), Ahnsorge et al.
patent: WO-9808525 (1998-03-01), None
patent: WO-9808526 (1998-03-01), None
H. Bradlow “Extraction of Steroid Conjugates With a Neutral Resin”Steroids(1968) pp. 265-272.
International Search Report.

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