Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a tree having matured height of...
Reexamination Certificate
2005-05-24
2005-05-24
Tate, Christopher R. (Department: 1654)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from a tree having matured height of...
C424S725000, C424S777000, C514S054000
Reexamination Certificate
active
06896914
ABSTRACT:
The invention is directed to a dietary supplement which contains mannoheptulose. Mannoheptulose occurs naturally in avocado fruit. The dietary supplement and its method of use can lower serum insulin levels and lower a subject's weight. The dietary supplement in its disclosed form includes a controlled release system for mannoheptulose. The dietary supplement may also include one or more amino acids.
REFERENCES:
patent: 4372948 (1983-02-01), Yoshikumi et al.
patent: 5344824 (1994-09-01), Ohkuma et al.
patent: 6319510 (2001-11-01), Yates
patent: 20020035071 (2002-03-01), Pitha et al.
Raonimalala et al. Annales de la Nutrition et de l'Alimentation. 1980. vol. 34 (4), pp. 735-744, CAPLUS abstract enclosed.*
W. Langhans, & E. Scharrer, Changes in Food Intake and Meal Patterns Following Injection of D-Mannoheptulose in Rats, Behavioral and Neural Biology 38, pp. 269-286, (1983).
W. Nelkin, Diabetogenicity of Ketoheptoses, II, Relative Potencies, Acta Physiologica Academiae Scientarium Hungaricae, Tomus 41 (2), pp. 175-177, (1972).
W. Nelkin, Diabetogenicity of Ketoheptoses, III,Modification of Structure, Acta Physiologica Acadamiae Scientarium Hungaricae, Tomus 41, pp. 179-181, (1972).
Josef K. Viktora, et al., Effect of Ingested Mannoheptulose in Animals and Man, Metabolism 18, No. 2, pp. 87-102, (1969).
Brian F. Johnson & Frederick W. Wolf, Trial of Mannoheptulose in Man, Metabolism 19, No. 5, pp. 354-362, (1970).
A. Lev-Ran, et al., Effect of Intravenous Infusion of D-Mannoheptulose on Blood Glucose, Journal of Endocrinolgoy 47, pp. 137-138, (1970).
Annonymous, Nutrition Reviews 27, No. 7, pp. 206-208, (1969).
E. P. Paulsen, Mannoheptulose and Insulin Inhibition, Annuals New York Academy of Science 150, pp. 455-456, (1968).
Milan Rezek, et al., Insulin Dependence of Paradoxial Overeating: Effect on Mannoheptulose, Somatostatin, and Cycloheximide, American Journal of Physiol 236 (3), pp. E205-E211, (1979).
Saul Genuth & Harold E. Lebovitz, Stimulation of Insulin Release by Corticotropin, Endocrinology 76, No. 6, pp. 1093-1099, (1965).
F. B. La Forge, D-Mannoketoheptose, A New Sugar From the Avocado, The Journal of Biological Chemistry 28, pp. 511-527, (1916-1917).
Thomas Laedtke, et al., Overnight Inhibition of Insulin Secretion Restores Pulsatility and Proinsulin/Insulin Ratio in Type 2 Diabetes, American Journal Physiol Endocrinol Metab. 279, pp. E520-E528, (2000).
Saul M. Genuth, M.D., Plasma Insulin and Glucose Profiles in Normal, Obese, and Diabetic Persons, Annals of Internal Medicine 79, pp. 812-822, (1973).
Paul B. Beeson, M.D.and Walsh McDermott, M.D., Textbook of Medicine 14th Edition, pp. 1375-1386, (1975).
Edna M. Montgomery and C. S. Hudson, The Synthesis of D-Mannoheptulose, and the Preparation of Some of its Derivatives, The Journal of the American Chemical Society 61, pp. 1654-1658, (1939).
Nelson K. Richtmyer, D-Manno-Heptulose, Isolation Form the Avocado, Methods in Carbohydrate Chemistry 1,pp. 173-176, (1962).
Timothy M. Chan and J. P. Dehaye, Hormone Regulation of Glucose Metabolism in the Genetically Obese-Diabetic Mouse (db/db), Diabetes 30, pp. 211-218 (1981).
K. Hermansen, Pancreatic D-Cell Recognition of D-Glucose, Diabetes 30, pp. 203-210, (1981).
E. Simon, Ph.D. and P. F. Kraicer, Ph.D., The Blockade of Insulin Secretion by Mannoheptulose, Israel Journal of Medical Science 2, No. 6, pp. 785-799, (1966).
B. Johnson, et al., The Efficacy of Oral Mannoheptulose in Monkey and Man, Diabetes 18, Suppl. 1, p. 360, (1969).
U.S. patent application Ser. No. 09/950,052, Pitha et al., filed Mar. 21, 2002.
Raonimalala, A.F., et al., Action Des Glucides Solubles Du Fruit De L'Avocatier (Persea Gratissima Gaertner) Sur L'Utilisation Du Calium Chez Le Rat, Annales De La Nutrition Et De L'Alimentation (1980), 735-44, 34(4).
Chapnick David I.
Chapnick Linda G.
Powell Goldstein Frazer & Murphy LLP
Rhee Bernard
Tate Christopher R.
LandOfFree
Method for normalizing insulin levels does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for normalizing insulin levels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for normalizing insulin levels will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3426082