Method for non-invasive blood analyte measurement with improved

Details Method for non-invasive blood analyte measurement with improved Method for non-invasive blood analyte measurement with improved

1998-10-19

2000-11-28

Winakur, Eric F.

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

2524081, A61B 500

Patent

active

061528765

ABSTRACT:
A method for non-invasively measuring the concentration of an analyte, particularly blood analyte in blood. The method utilizes spectrographic techniques in conjunction with an improved optical interface between a sensor probe and a skin surface or tissue surface of the body containing the blood to be analyzed. An index-matching medium is disclosed to improve the interface between the sensor probe and skin surface during spectrographic analysis. In a preferred embodiment, the blood analyte concentration in blood is quantified utilizing a partial squares analysis relative to a model incorporating analysis of plural known blood samples.

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