Method for monitoring the effects of chemotherapeutic agents on

Details Method for monitoring the effects of chemotherapeutic agents on Method for monitoring the effects of chemotherapeutic agents on

1995-10-02

1998-12-15

Tran, Lien

Chemistry: analytical and immunological testing

Optical result

426 63, 426 64, 426805, 426811, 426813, 422 8207, G01N 2100

Patent

active

058495959

ABSTRACT:
A method for monitoring the effects of a chemotherapeutic agent on a neoplasm medium. The method is premised on the discovery that chemotherapeutic agent, such as retinoic acid, affects the fluorescence spectroscopy of neoplasmic media and that such differences can be monitored, for example, by comparing the spectral profiles, spectral peaks, and spectral bandwidths of fluorescence at various wavelengths of the medium before and after administration of the chemotherapeutic agent. Differences in the excitation spectroscopy of the medium can also be used to monitor the effects of the agent.

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