Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2008-08-07
2010-06-01
Shibuya, Mark L (Department: 1641)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C435S007100, C435S007930, C436S518000, C422S067000
Reexamination Certificate
active
07728112
ABSTRACT:
A method for improving the diagnostic assessment of cartilage degenerative processes, and to provide means of monitoring the effects of therapeutical measures taken towards arthritic diseases in most mammals utilizes an immunoassay to detect fragments of collagen type II resulting from collagenase activity comprising an antibody directed against an epitope comprised in the amino acid sequence HRGYPGLDG (SEQ ID NO:1), located in the helical region of collagen type II.
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Christgau Stephan
Deberg Michelle
Henrotin Yves
Reginster Jean-Yves
Foster Christine
Jacobson & Holman PLLC
Shibuya Mark L
Universite de Liege
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