Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2006-07-18
2006-07-18
Wax, Robert A. (Department: 1653)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C435S007100, C514S018700, C530S331000
Reexamination Certificate
active
07078165
ABSTRACT:
A method for modulating Nod 1 activity wherein said method comprises the steps of providing cells expressing a functional Nod 1; and bringing said cells into contact with a molecule related to compositions comprising a molecule related to MTP and use of a molecule related to MTP for modulating inflammation and/or apoptosis
REFERENCES:
patent: 2002/0197693 (2002-12-01), Bertin
International Search Report in corresponding PCT/IB2004/001318.
Stephen E. Girardin et al.; Nod2 is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection; The Journal of Biological Chemistry, vol. 278, No. 11, pp. 8869-8872 (2003).
Naohiro Inohara et al.; Human Nod1 Confers Responsiveness to Bacterial Lipopolysaccharides; The Journal of Biological Chemistry, vol. 276, No. 4, pp. 2551-2554 (2001).
Tsuyoshi Uehara and James T. Park; Identification of MpaA, an Amidasein Escherichia colithat Hydrolyzes the γ-D-Glutamyl-meso-Diaminopimelate Bond in Murein Peptides; Journal of Bacteriology, vol. 185, No. 2, pp. 679-682 (2003).
Stephen E. Girardin et al.; Peptidoglycan Molecular Requirements Allowing Detection by Nod1 and Nod2; The Journal of Biological Chemistry, vol. 278, No. 43, pp. 41702-41708 (2003).
Boneca Ivo
Girardin Stephen
Philpott Dana
Sansonetti Philippe
Finnegan Henderson Farabow Garrett & Dunner LLP
Institut Pasteur
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