X-ray or gamma ray systems or devices – Specific application – Absorption
Reexamination Certificate
2008-11-07
2009-10-27
Kiknadze, Irakli (Department: 2882)
X-ray or gamma ray systems or devices
Specific application
Absorption
C378S147000
Reexamination Certificate
active
07609811
ABSTRACT:
The present invention provides an intensity modulated radiation therapy (IMRT) method for treating a target region that minimizes the tongue and groove effect. By minimizing that effect, striping in the final delivered fluence is reduced, which improves the overall quality of the radiation delivery. In the method, compensating functions Ci(x) are added to leaf coordinates ai(x) and bi(x) for all of the leaf pairs i in a leaf sequence algorithm, where Ci(x) is chosen to match the mechanical limitations of the MLC and to minimize non-weighted or weighted sums of the tongue and groove effects, where the weighting is time-dependent, position-dependent, or time- and position-dependent, or to minimize the total treatment time, changes to the original MLC sequence, or the tongue and groove effect distribution variance in spatial or temporal coordinates.
REFERENCES:
patent: 5847403 (1998-12-01), Hughes et al.
patent: 6661871 (2003-12-01), Siochi
patent: 7257196 (2007-08-01), Brown et al.
patent: 2005/0254623 (2005-11-01), Kamath et al.
patent: 2007/0127624 (2007-06-01), Seeber et al.
Pesola Katja Marika
Siljamaki Sami Pekka
Kiknadze Irakli
Townsend and Townsend / and Crew LLP
Varian Medical Systems International AG
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