Method for minimizing disturbances in circadian rhythms of bodil

Details Method for minimizing disturbances in circadian rhythms of bodil Method for minimizing disturbances in circadian rhythms of bodil

1984-05-18

1986-07-15

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3140

Patent

active

046007237

ABSTRACT:
Disturbances in circadian rhythms of bodily performance and function, as may occur for example in transfer of work patterns from day to night-shift, or rapid crossing of several time zones in an aircraft ("jet lag") are treated by administration of melatonin. Alleviation or prevention of ill effects associated with disturbance of circadian rhythms is achieved by administration of melatonin in specified ways which are varied to suit particular needs and circumstances.

REFERENCES:
Chemical Abstract, 96, 156305w.
Merck Index, 1983, p. 828, No. 5634.
Arendt, J. and Marks, V., "Physiological Changes Underlying Jet Lag", British Medical Journal, 16 Jan. 1982, pp. 144-146.
Redman, J., Armstrong, S., and Ng, K. T., "Free-Running Activity Rhythms in the Rat: Entrainment by Melatonin", Science, vol. 219, pp. 1089-1091, 4 Mar. 1983.
Cramer, H., et al., "On the Effects of Melatonin on Sleep and Behavior in Man", Advances in Biochemical Psychopharmacology, vol. 11, pp. 187-191, 1974.
Carman, J. S., et al., "Negative Effects of Melatonin on Depression", Am. J. Psychiatry, 133:10, pp. 1181-1186, Oct. 1976.
Vollrath, L., et al., "Sleep Induction by Intranasal Application of Melatonin", Advances in Bioscience, 29, pp. 327-329, 1981.
Norlund, J. J., and Lerner, A. B., "The Effects of Oral Melatonin on Skin Color and on the Release of Pituitary Hormones", JCE & M, vol. 45, No. 4, pp. 768-774, 1977.
Anton-Tay, F. et al., "On the Effect of Melatonin Upon Human Brain. Its Possible Therapeutic Implications", Life Sciences, vol. 10, Part I, pp. 841-850, 1971.
Fevre-Montange et al., J. Clin. Endocrinol. Metab. 52 642-649 (1981).
Akerstedt et al., Biological Psychiatry 17 547-554 (1982).
Cramer et al., 1st. Europ. Congr. Sleep Res. Based 1972, pp. 488-491.
Reinhard et al., 2nd Europe. Congr. Sleep Res., Rome 1974, pp. 518-222.
Pavel et al., Adv. Biosciences 29 343-374(1981).
Chem. Abst. 94 (1981) 171,981 R.
Chem. Abst. 97 (1982) 33783 D.
Chem. Abst. 81 (1974) 86396R and 84(1976), 54600Y and 94(1981) 171799n.

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