Method for microbial production of xylitol from arabinose

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...

Reexamination Certificate

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C435S320100, C435S183000, C435S189000, C435S233000, C435S132000, C435S252100, C435S252330, C435S254100, C435S252300, C536S023200

Reexamination Certificate

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07977083

ABSTRACT:
Recombinant microorganisms are useful for producing xylitol by fermentation of arabinose. The recombinant microorganisms are produced by transformation of host microorganisms with heterologous polynucleotide sequences coding for each of L-xylulose reductase, D-tagatose 3-epimerase, and L-arabinose isomerase, which transformants express the heterologous polynucleotides at a sufficient functional level to be effective to produce xylitol from arabinose. Production of xylitol is effected by contacting these recombinant microorganisms with a substrate comprising arabinose under conditions effective to produce xylitol from arabinose.

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patent: 2006/0110809 (2006-05-01), Taylor
patent: 1284564 (2001-02-01), None
Brenda. EC 1.1.1.10, EC 5.3.1.4, and EC 2.7.1.16. obtained from the internet on Dec. 3, 2009.
Datsenko et al. PNAS. vol. 97, No. 2, pp. 6640-6645, 2000.
Richard et al. Production of ethanol from L-arabinose by Saccharomyces cerevisiae containing a fungal L-arabinose pathway. FEMS Yeast Res. Apr. 2003;3(2):185-9.

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