Method for measuring tissue morphology

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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Reexamination Certificate

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06922583

ABSTRACT:
The present invention relates to systems and methods for measuring one or more physical characteristics of material such as tissue using optical radiation. The system can use light that is scattered by a tissue layer to determine, for example, the size of nuclei in the tissue layer to aid in the characterization of the tissue. These methods can include the use of fiber optic devices to deliver and collect light from a tissue region of interest to diagnose, for example, whether the tissue is normal or precancerous.

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Newton, R.G.,Scattering Theory of Waves and Particles, Second Ed. Chapter 2, “Spherically Symmetric Scatters”, pp. 30-53 Chapter 3, “Limiting Cases and Approximations”, pp. 54-78.

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