Method for measuring the rate of cell reproduction by...

Details Method for measuring the rate of cell reproduction by... Method for measuring the rate of cell reproduction by...

2005-04-26

2005-04-26

Canella, Karen A. (Department: 1642)

Chemistry: analytical and immunological testing

Biological cellular material tested

C436S164000, C356S246000, C356S301000, C356S318000, C356S436000, C356S440000, C356S441000

Reexamination Certificate

active

06884624

ABSTRACT:
A method of detecting cancer using a laser biocavity having a semiconductor laser including a microchannel through which cells in fluid traverse, comprising determining the laser wavelength of the laser biocavity with only fluid in the microchannel; determining the wavelength shift of the biocavity when each cell passes through the microchannel; and determining the percentage of cells in G2 phase from the wavelength shift of the cells; wherein an increased percentage of G2 phase cells is an indication of cancer.

REFERENCES:
patent: 798386 (1997-03-01), None
The abstract of Uhal et al (Aerican Respiratory Disease, 1991,vol. 143, No. 4, part 2, p. A301).*
Luther et al (Cytometry, 1996, vol. 23, pp. 272-278).*
Meissner et al, SPIE, 1995, vol. 2399, pp. 561-570.*
Gourley, Nature Medicine, 1996, vol. 2, pp. 942-944.*
Gourley, Optics and Photonics News, 1997, vol. 8, pp. 31-36.*
Gourley, Sandia National Laboratories Technical Report, 1997 (SAND97-1988), pp. 1-26.

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