Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2005-05-26
2008-12-23
Winakur, Eric F (Department: 3768)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S410000, C600S558000, C382S128000
Reexamination Certificate
active
07469159
ABSTRACT:
Neurovascular uncoupling that causes fMRI data to underestimate viable neuronal activity in the brain is detected and indicated to assist in pre-surgical planning. Tasks associated with the cortical region in question are performed while the fMRI measurement of brain activity is measured and the same tasks are performed while task performance is measured directly. Neurovascular uncoupling is detected and indicated by comparing the results of fMRI measurement and direct measurement.
REFERENCES:
patent: 5459536 (1995-10-01), Shalon et al.
patent: 6260021 (2001-07-01), Wong et al.
patent: 6430431 (2002-08-01), De Yoe
patent: 6527391 (2003-03-01), Heijl et al.
Hirsch et al., An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions, Neurosurgery, vol. 47, No. 3, Sep. 2000, pp. 711-722.
John L Ulmer et al, Lesion-Induced Pseudo-Dominance at Functional Magentic Resonance Imaging: Implications for Preoperative Assessments, Neurosurgery, vol. 55, No. 3, Sep. 2004, pp. 569-581.
Andrei I. Holodny, et al, The Effect Of Brain Tumors On BOLD Functional MR Imaging Activation In The Adjacent Motor Cortex: Implications For Image-guided Neurosurgery, AJNR AM J Neuroradiol 21:1415-1422, Sep. 2000.
Young-Jun Lee et al, The Role Of Functional MR Imaging In Patients With Ischemia In The Visual Cortex, AJNR Am J Neuroradiol 22:1043-1049, Jun./Jul. 2001.
Stephane Lehericy et al, Arteriovenous Brain Malformation: Is Functional MR Imaging Reliable For Study Language Reorganization In Patient? Initial Observations, Radiology, vol. 223, No. 3, Jun. 2002, pp. 672-682.
Axel Schreiber et al, The Influence Of Gliomas and Nonglial Space-Occupying Lesins On Blood-Oxygen-Level-Dependent Contrast Enhancement, AJNR Am J Neuroradiol 21:1055-1063, Jun./Jul. 2000.
John L. Ulmer et al, Pseudo-Reorganization Of Language Cortical Function At fMR Imaging: A Consequence of Tumor-Induced Neurovascular Uncoupling, AJNR Am J Neuroradiol 24:213-217, Feb. 2003.
DeYoe Edgar
Ulmer John L.
Fernandez Katherine L
Quarles & Brady LLP
The MCW Research Foundation Inc.
Winakur Eric F
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