Method for measuring human cholesterol absorption using metaboli

Details Method for measuring human cholesterol absorption using metaboli Method for measuring human cholesterol absorption using metaboli

1992-09-30

1995-07-11

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving cholesterol

435 19, 435968, 436 13, 436 16, 436 56, 436 57, 436504, 436804, 424 111, 424529, 424530, 514 54, 514 55, 514 57, 514 59, C12Q 160, G01N 3100, A01N 4304

Patent

active

054320585

ABSTRACT:
This invention is a method for measuring the ability of a human to absorb cholesterol. The method uses two different cholesterol tracers, the first injected into the blood stream and the second ingested by the human subject. After a waiting period a blood sample is taken from the human subject and analyzed to determine percent cholesterol absorption based on the actual amounts of the two naturally occurring, metabolically stable cholesterol tracers in the blood. The method of this invention is useful in identifying human subjects as high cholesterol absorbers and thereafter administering therapeutic agents to the subject that inhibit the absorption of cholesterol.

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