Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Blood serum or blood plasma standard or control
Patent
1982-05-03
1984-11-20
Bernstein, Hiram H.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Blood serum or blood plasma standard or control
435 34, C12Q 106
Patent
active
044839260
ABSTRACT:
This invention encompasses methods and reagents for inactivation of bacterial growth inhibitors present in blood, serum or plasma. It has been found that salicylates and closely related compounds will neutralize bacterial growth inhibitors present in the blood of many patients. The addition of salicylate to conventional growth medium also provides a reagent for monitoring the antibiotic levels in blood by enabling measurement of the effect of the antibiotic against a standard test organism without interference from the bacterial growth inhibitor present in sera.
REFERENCES:
patent: 3671399 (1972-06-01), Cekoric et al.
patent: 4340679 (1982-07-01), Fukui et al.
Levine et al., A Compilation of Culture Media Williams & Wikins Co., 1930, Baltimore.
Fukui George M.
Spencer Herbert J.
Williams, II Laurens R.
Abbott Laboratories
Bernstein Hiram H.
Katz Martin L.
Wilcox James L.
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