Chemistry: analytical and immunological testing – Involving kinetic measurement of antigen-antibody reaction
Patent
1995-01-13
1997-10-21
Adams, Donald E.
Chemistry: analytical and immunological testing
Involving kinetic measurement of antigen-antibody reaction
436 64, 436 65, 436164, 436518, 436531, 436533, 436805, 436813, 436814, G01N 33557
Patent
active
056795815
ABSTRACT:
There are provided a method and an apparatus for measuring an immunologically active material by physically or chemically immobilizing material immunologically active to a material to be measured of a specimen to the dehydrated solid fine particles, providing a desirable dispersion comprising said immunologically active material immobilized to said solid fine particles and said specimen in a liquid medium, reacting them to cause a reaction mixture in an agglutinated state and optically measuring said agglutinated state of the reaction mixture to thereby quantitatively determine the content of said material to be measured with an improved accuracy.
REFERENCES:
patent: 4419453 (1983-12-01), Dorman et al.
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J. M. Singer et al., "The Latex Fixation Test," American Journal of Medicine, Dec. 1956, pp. 888-892.
A. Faure et al., "Quantitative Study of Tests Using Latex Particles Coated with Proteins or Peptides," Protides Biol. Fluids, Proc. Colloq., 2589 (1972), pp. 589-593.
Immobilization Enzymes, ed. Ichiro Chihata Kodansha (1975), pp. 10-43 (please see p. 16 of the specification where this reference is cited and discussed, no English translation was available).
Immunological Procedure VIII, Bunko-do 2401 (1979), pp. 2401-2411 (please see p. 26 of the specification where this reference is cited and discussed, no English translation was available).
Diagnostic Test 30, vol. 30, No. 11, pp. 1258-1265 (please see p. 30 of the specification where this reference is cited and discussed, no English translation was available).
Miyazaki Takeshi
Okamoto Tadashi
Sakuranaga Masanori
Tanaka Kazumi
Adams Donald E.
Canon Kabushiki Kaisha
Stucker Jeffrey
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