Method for manufacturing gelatin with reduced endotoxin...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.

Reexamination Certificate

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C530S354000

Reexamination Certificate

active

07855273

ABSTRACT:
A method of manufacturing gelatin with reduced endotoxin content. The method comprises processing a starting material gelatin-containing solution containing gelatin and an endotoxin with an ultrafiltration film having a molecular weight cut-off falling within a range of from 20,000 to 300,000 and having a molecular weight cut-off capable of passing at least a portion of the gelatin contained in the starting material gelatin-containing solution to obtain a permeate that is a gelatin-containing solution with a reduced endotoxin content. A gelatin having an average molecular weight falling within a range of 1,000 to 300,000 and an endotoxin content of less than 1 EU/mL per 1.0 percent of protein.

REFERENCES:
patent: 4082737 (1978-04-01), McGregor et al.
patent: 4307013 (1981-12-01), Ohtsuka et al.
patent: 4374063 (1983-02-01), Consolazio et al.
patent: 56-68607 (1981-09-01), None
patent: 58-73371 (1983-05-01), None
patent: 2004-089448 (2004-03-01), None
patent: 2004-300077 (2004-10-01), None
patent: 2005-289841 (2005-10-01), None
patent: 2007-211170 (2007-08-01), None
Petsch et al., “Endotoxin removal from protein solutions,” J. of Biotechnology, 76, 2000, pp. 97-119.
Pausa et al., “The endothelium is an extrahepatic site of synthesis of the seventh component of the complement system,” Clin. Exp. Immunol. 121, 2000, pp. 69-76.
Charles P. Gerba et al, Endotoxin Removal by Charge-Modified Filters, Applied and Environmetnal Microbiology, Dec. 1985, pp. 1375-1377, vol. 50, No. 6.
Kathleen J. Sweadner, et al, Fileration Removal of Endotoxin (Pyrogens) in Solution in Different States of Aggregation, Applied and Environmetnal Microbiology, Oct. 1977, pp. 382-385, vol. 34, No. 4.
Yoshitaka Kanayama et al, Development of Low Endotoxin Gelatin for Regenerative Medicine, Biol. Pharm. Bull. 30(2) 237-241 (Feb. 2007).
European Search Report, 07004405.2, mailed May 10, 2007.
Gorbet et al: “Endotoxin: The uninvited guest” Biomaterials, Elsevier Science Publisher BV., Barking, GB, vol. 26, No. 34, Dec. 2005, pp. 6811-6817, XP005000771 ISSN: 0142-9612.

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