Method for manufacturing buccal delivery device

Details Method for manufacturing buccal delivery device Method for manufacturing buccal delivery device

1995-07-10

1997-07-22

Lovering, Richard D.

Coating processes

Medical or dental purpose product; parts; subcombinations;...

Particulate or unit-dosage-article base

34284, 34287, 261DIG26, 424430, 424433, 424434, 424435, 514182, 514945, 514965, A61J 300, A61K 919

Patent

active

056501927

ABSTRACT:
The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous, enclosed mixing device capable of operating under pressure. The devices of the invention, which comprise a lyophilized foam and an active ingredient, have a dissolution time of at least about 8 hours, and preferably at least about 24 hours, and can provide for the sustained and/or controlled release of an active ingredient for up to about 24 hours.

REFERENCES:
patent: 3309779 (1967-03-01), Ginnette et al.
patent: 3939260 (1976-02-01), Lafon
patent: 4642903 (1987-02-01), Davies
patent: 4948580 (1990-08-01), Browning
patent: 5354558 (1994-10-01), Britton et al.
patent: 5458884 (1995-10-01), Britton et al.

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