Method for manufacture of biodegradable drug donor and drug dono

Details Method for manufacture of biodegradable drug donor and drug dono Method for manufacture of biodegradable drug donor and drug dono

1984-08-02

1987-11-03

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

A61K 900, A61K 922

Patent

active

047042680

ABSTRACT:
A method for the manufacture of a biodegradable drug donor capable of gradually releasing a drug to a living body and the drug donor made thereby are described, said method comprising dissolving a chitin in a solvent to thereby prepare a dope, bringing said dope into contact with a liquid coagulant to thereby form a swelled mass containing said chitin, impregnating said chitin-containing swelled mass with a solution containing a drug, and subsequently drying the impregnated swelled mass.

REFERENCES:
patent: 3911098 (1975-10-01), Capozza
patent: 3989535 (1975-10-01), Capozza
patent: 4029727 (1977-06-01), Austin et al.
patent: 4059457 (1977-11-01), Austin
R. A. A. Mozzarelli Chitin, pp. 58-65, Pergamon Press (1977).
Filar and Wirick, "Bulk and Solution Properties of Chitosan", Proceedings of the First International Conference on Chitin/Chitosan", (Mozzarelli and Pauser Eds. 1978), U.S. Department of Commerce, National Technical Information Service, PB-285640.

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