Method for making water-soluble elastin hydrolyzates

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

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424359, C12D 1306

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active

041793331

ABSTRACT:
A water-soluble hydrolyzate of elastin, suitable for cosmetological use, is disclosed as is a method for making a water-soluble elastin hydrolyzate from starting materials containing elastin which comprises first subjecting said starting material to acid treatment at a pH below about 4 and at an elevated temperature and then enzymatically degrading the acid-treated material, while in comminuted form, in an aqueous bath in the presence of urea, with an alkaline proteinase having an activity optimum in a range between pH 9 and pH 13, the initial pH of the enzymatic treatment being within the pH range optimum for the enzyme employed.

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patent: 2817342 (1957-12-01), Henkin
T. C. Cordon et al., Elastase Activity of Some Enzymes as Related to their Depilatory Action, the Journal of the American Leather Chemists Association, vol. LVI, No. 2, 1961; pp. 68-79.
Chemical Abstracts, 12448g; vol. 65; 1966.
Chemical Abstracts, 82455h; vol. 76; 1972.

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