Plastic and nonmetallic article shaping or treating: processes – Formation of solid particulate material directly from molten... – Coated particles
Reexamination Certificate
2007-11-06
2007-11-06
Theisen, Mary Lynn (Department: 1732)
Plastic and nonmetallic article shaping or treating: processes
Formation of solid particulate material directly from molten...
Coated particles
C264S005000, C264S013000, C264S014000
Reexamination Certificate
active
10399595
ABSTRACT:
The invention concerns a method for making very fine particles containing at least an active principle inserted in a host molecule and a device for implementing said method. The method is characterized in that it consists in forming a solution of the active principle in a first liquid solvent and of a product formed by the host molecules in a second liquid solvent, then in contacting the resulting solutions with a supercritical pressure fluid, so as to precipitate the host molecules which are dissolved therein.
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patent: WO99/59710 (1999-11-01), None
patent: WO 00/27844 (2000-05-01), None
Jung, J. et al. “Particle design using supercritical fluids: Literature and patent survey” Journal of Supercritical Fluids, PRA Press, US, vol. 20, No. 3, Aug. 2001, pp. 179-219.
Kamihira, M. et al. “Formation of inclusion complexes between cyclodextrins and aromatic compounds under pressurized carbon dioxide” J Ferment Bioeng, 1990 69 (6) pp. 350-353.
Subrananiam, B. et al . “Pharmaceutical processing with supercritical carbon dioxide” Journal of Pharmaceutical Sciences, US, vol. 86, No. 8, Aug. 1, 1997 pp. 885-890.
Van Hees, T. et al. “Application of supercritical carbon dioxide for the preparation of a piroxicam-beta-cyclodextrin inclusion compound” Pharmaceutical Research Dec. 1999 16 (12) 1864-1870.
Van Hees, T. et al. “Inclusion of piroxicam into beta- cyclodextrin by means of supercritical carbon dioxide: thermal, spectroscopic and physicochemical studies” Journal de Pharmacie de Belgique (Jan.-Feb. 2000) 55 (1) pp. 30-31.
Fabing Isabelle
Jung Jennifer
Leboeuf Fabrice
Perrut Michel
Separex (Societe Anonyme)
Theisen Mary Lynn
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