Method for making therapeutic enzyme compositions

Details Method for making therapeutic enzyme compositions Method for making therapeutic enzyme compositions

1980-01-28

1981-08-25

Warden, Robert J.

Chemistry: molecular biology and microbiology

Condition responsive control process

435214, C12Q 300, C12N 974

Patent

active

042860563

ABSTRACT:
This is an improved method for producing activated prothrombin complex concentrate which comprises controlling the degree of activation by determining the activation state of the starting material and then varying at least one of the activation conditions in accordance with analyses of the progress of activation of the starting material to arrive at a predetermined activation level.

REFERENCES:
patent: 3560475 (1971-02-01), Fekete et al.
patent: 4160025 (1979-07-01), Eibl et al.
Kurczynski et al., New England Journal of Medicine, vol. 291, No. 4, pp. 164-167; 1974.
Y. Sultan et al., New England Journal of Medicine, vol. 291, No. 20, p. 1087; 1974.

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