Method for making quinoline carboxylic acids or naphthyridine ca

Details Method for making quinoline carboxylic acids or naphthyridine ca Method for making quinoline carboxylic acids or naphthyridine ca

1995-05-26

1997-02-11

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546156, C07D21556, C07D47102

Patent

active

056022549

ABSTRACT:
The present invention provides a method of making quinolone carboxylic acids or naphthyridine carboxylic acids in free base form, the method comprising dissolving a quinolone carboxylic acid salt or naphthyridine carboxylic acid salt in a solvent system to form a solution; combining the solution containing the quinolone carboxylic acid salt or naphthyridine carboxylic acid salt with a calcium salt in an amount in the range of about 0.01% to about 5.0% by weight of the quinolone carboxylic acid salt or naphthyridine carboxylic acid salt and a base, the combination resulting in the formation of a precipitate; and collecting the precipitate. Also provided is a solid bulk pharmaceutical chemical composition which is the product resulting from the precipitation.

REFERENCES:
patent: 4146719 (1979-03-01), Irikura
patent: 4563459 (1986-01-01), Grohe et al.
patent: 4771054 (1988-09-01), Domagala et al.
patent: 4851418 (1989-07-01), Sanchez
patent: 4867901 (1989-09-01), Bosch et al.
patent: 4950787 (1990-08-01), Griffith et al.
patent: 4973590 (1990-11-01), Preiss et al.
patent: 5290794 (1994-03-01), Mehta et al.
Kirk-Othmer, Encyclopedia of Chem. Tech. 3ed., vol. 10, pp. 284-297 and pp. 489-499 (1980).

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