Method for making pyrazolo[1,5-c]quinazoline derivatives and rel

Details Method for making pyrazolo[1,5-c]quinazoline derivatives and rel Method for making pyrazolo[1,5-c]quinazoline derivatives and rel

1977-12-02

1979-12-18

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

26032611R, 548378, 424251, C07D48704, A61K 31505

Patent

active

041795610

ABSTRACT:
Compounds are provided having the structure ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different and R.sup.1 is hydrogen, alkyl of 1-3 carbons, phenyl optionally substituted by R.sup.4 or ##STR2## R.sup.2 is ##STR3## hydrogen, lower alkyl or phenyl optionally substituted by R.sup.4 with the proviso that at least one of R.sup.1 and R.sup.2 is ##STR4## R.sup.3 is hydrogen, lower alkyl, benzyl or phenyl optionally substituted by R.sup.4 ; and R.sup.4 and R.sup.5 are the same or different and represent hydrogen, lower alkyl, lower alkoxy, alkanoyloxy, benzyloxy, benzyloxy having a single mono-lower alkoxy substituent, hydroxy, halogen (Cl, Br and F), nitro, and trifluoromethyl; R.sup.6 is hydrogen, lower alkyl, alkanoyl, aroyl, aralkanoyl, aralkyl or phenyl; and R.sup.7, R.sup.8, m and n are as defined hereinafter.

REFERENCES:
patent: 3897434 (1975-07-01), Katner
patent: 3903106 (1975-09-01), Katner

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