Method for making intermediates useful in the synthesis of retro

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitriles

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Other Related Categories

560 27, 560115, 560159, 556410, 556412, C07D25300

Type

Patent

Status

active

Patent number

056485115

Description

ABSTRACT:
A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide or cyanohydrin from a chiral alpha amino aldehyde.

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