Method for making intermediates useful in synthesis of retrovira

Details Method for making intermediates useful in synthesis of retrovira Method for making intermediates useful in synthesis of retrovira

1996-09-13

2000-02-08

Owens, Amelia

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C21100

Patent

active

060229969

ABSTRACT:
A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

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