Method for making hydrophobic polymeric microparticles

Details Method for making hydrophobic polymeric microparticles Method for making hydrophobic polymeric microparticles

1993-09-21

1996-03-19

Barry, Chester T.

Plastic and nonmetallic article shaping or treating: processes

Formation of solid particulate material directly from molten...

Utilizing centrifugal force or rotating forming zone

264 9, 264 11, 264 12, 264 14, B29B 900

Patent

active

055001610

ABSTRACT:
A method for the preparation of microparticles, and the product thereof, that includes dispersing a substantially water insoluble non-ionic or ionic polymer in an aqueous solution in which the substance to be delivered is also dissolved, dispersed or suspended, and then coagulating the polymer together with the substance by impact forces to form a microparticle. In an alternative embodiment, the microparticle is formed by coagulation of an aqueous polymeric dispersion through the use of electrolytes, pH changes, organic solvents in low concentrations (the minimal amount necessary to break up the dispersion), or temperature changes to form polymer matrices encapsulating biological materials.

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