Method for making homozygous genetic modifications

Multicellular living organisms and unmodified parts thereof and – Method of making a transgenic nonhuman animal

Reexamination Certificate

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C800S025000

Reexamination Certificate

active

07659442

ABSTRACT:
Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.

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