Method for making carbamazephine derivative

Details Method for making carbamazephine derivative Method for making carbamazephine derivative

1997-07-25

1998-12-22

Nutter, Nathan M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 28, 562435, 562442, 562443, C07C20500, C07C20700, C07C22900, C07C26100

Patent

active

058521992

ABSTRACT:
The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C.dbd.O, CH.sub.2 or SO.sub.2 ; Y is C.dbd.O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.

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Wang, et al., Chemical Abstracts; Regents and Method for Determining Ligands on a sample of Biological Liquids; 98:2496;1983.

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