Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-08-19
1988-09-20
Fan, Jane T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549283, 549311, 549302, C07D31176
Patent
active
047727284
ABSTRACT:
A method for making a bicyclic lactone comprising heating under aqueous acidic conditions a beta, gamma unsaturated cyclic nitrile and an aldehyde, for a length of time sufficient to convert at least a portion of the reactants to a bicyclic lactone of the formula ##STR1## wherein R.sub.3 is --H; R.sub.4, R.sub.5, and R.sub.6 are independently selected from the group consisting of --H, --CH.sub.3 ; R.sub.2 is selected from the group consisting of --H, --CH.sub.3, and --CH.sub.3, and --C.sub.2 H.sub.5 ; R.sub.8 is --H or --CH.sub.3 ; m is an integer from 1 to 5; o is 0, 1, 2, or 3; and p is 0, 1, or 2; provided that the sum of m+o+p is an integer from 3 to 5; either R.sub.3 or R.sub.8 together with R.sub.7 represents a carbon-carbon bond. The method uses commercially available and relatively inexpensive raw materials as reactants.
REFERENCES:
patent: 3480634 (1969-11-01), Finkelstein et al.
patent: 3936473 (1976-02-01), Symon et al.
patent: 4219449 (1980-08-01), Lenselink et al.
Korte et al., Tetrahedron 1959, vol. 6, pp. 201-216.
Coulston Craig W.
Korte Friedhelm
Korte Stephan
Angus Chemical Company
Fan Jane T.
LandOfFree
Method for making bicycle lactones from beta, gamma unsaturated does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for making bicycle lactones from beta, gamma unsaturated , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for making bicycle lactones from beta, gamma unsaturated will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1749578