Method for making a multi-stage drug delivery system

Details Method for making a multi-stage drug delivery system Method for making a multi-stage drug delivery system

1995-02-06

1997-10-07

Bawa, Raj

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424453, 424464, 424466, 424468, 424470, A61K 922

Patent

active

056745303

ABSTRACT:
A method of making a drug delivery system (10) includes the steps of filling a first water permeable capsule half with a drug and an osmotic agent and plugging an open-end (24) of the capsule (12). The method further includes the steps of disposing a water permeable film (30) over the capsule (12) and plug (28), filling a second capsule half (14) with a drug (18), and releasably mounting an open end (34) of the second capsule half (14) over the plugged end (24) of the first capsule half (12).

REFERENCES:
patent: 4773907 (1988-09-01), Urquhart et al.
patent: 4777049 (1988-10-01), Magruder et al.
patent: 4783337 (1988-11-01), Wong et al.
patent: 4865849 (1989-09-01), Conte et al.
Gennaro, A.R. (1985). Remington's Pharmaceutical Sciences. Mack Pub. Co., pp. 1625-1630 and 1638-1643.

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