Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-03-13
2009-12-01
Audet, Maury (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C424S001690
Reexamination Certificate
active
07625862
ABSTRACT:
The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
REFERENCES:
patent: 3518982 (1970-07-01), Timmins et al.
patent: 3925344 (1975-12-01), Mazur
patent: 3956259 (1976-05-01), Garcia et al.
patent: 4001200 (1977-01-01), Bonsen et al.
patent: 4001401 (1977-01-01), Bonsen et al.
patent: 4053590 (1977-10-01), Bonsen et al.
patent: 4061736 (1977-12-01), Morris et al.
patent: 4064118 (1977-12-01), Wong
patent: 4113853 (1978-09-01), Funakoshi et al.
patent: 4133874 (1979-01-01), Miller et al.
patent: 4179337 (1979-12-01), Davis et al.
patent: 4209300 (1980-06-01), Thibault
patent: 4301144 (1981-11-01), Iwashita et al.
patent: 4336248 (1982-06-01), Bonhard et al.
patent: 4377512 (1983-03-01), Ajisaka et al.
patent: 4401652 (1983-08-01), Simmonds et al.
patent: 4412989 (1983-11-01), Iwashita et al.
patent: 4439357 (1984-03-01), Bonhard et al.
patent: 4473494 (1984-09-01), Tye
patent: 4473496 (1984-09-01), Scannon
patent: 4526715 (1985-07-01), Kothe et al.
patent: 4529719 (1985-07-01), Tye
patent: 4532130 (1985-07-01), Djordjevich et al.
patent: 4584130 (1986-04-01), Bucci et al.
patent: 4598064 (1986-07-01), Walder
patent: 4600531 (1986-07-01), Walder
patent: 4650786 (1987-03-01), Wong
patent: 4670417 (1987-06-01), Iwasaki et al.
patent: 4710488 (1987-12-01), Wong
patent: 4738952 (1988-04-01), Ecanow et al.
patent: 4777244 (1988-10-01), Bonhard et al.
patent: 4826811 (1989-05-01), Sehgal et al.
patent: 4831012 (1989-05-01), Estep
patent: 4857636 (1989-08-01), Hsia
patent: 4861867 (1989-08-01), Estep
patent: 4900780 (1990-02-01), Cerny
patent: 4911929 (1990-03-01), Farmer et al.
patent: 4920194 (1990-04-01), Feller et al.
patent: 4987154 (1991-01-01), Long
patent: 5028588 (1991-07-01), Hoffman et al.
patent: 5041615 (1991-08-01), Hai et al.
patent: 5058416 (1991-10-01), Englehardt et al.
patent: 5061688 (1991-10-01), Beissinger et al.
patent: 5077036 (1991-12-01), Long
patent: 5080885 (1992-01-01), Long
patent: 5084558 (1992-01-01), Rausch
patent: 5114932 (1992-05-01), Runge
patent: 5115100 (1992-05-01), Wu et al.
patent: 5128452 (1992-07-01), Hai et al.
patent: 5194590 (1993-03-01), Sehgal et al.
patent: 5200323 (1993-04-01), Chang et al.
patent: 5217648 (1993-06-01), Beissinger et al.
patent: 5234903 (1993-08-01), Nho et al.
patent: 5239061 (1993-08-01), Fronticelli et al.
patent: 5248766 (1993-09-01), Nelson et al.
patent: 5250665 (1993-10-01), Kluger et al.
patent: 5264555 (1993-11-01), Shorr et al.
patent: 5281579 (1994-01-01), Estep
patent: 5295944 (1994-03-01), Teicher et al.
patent: 5296465 (1994-03-01), Rausch et al.
patent: 5312808 (1994-05-01), Shorr et al.
patent: 5334705 (1994-08-01), Bonaventura et al.
patent: 5334706 (1994-08-01), Przybelski
patent: 5344393 (1994-09-01), Roth et al.
patent: 5349054 (1994-09-01), Bonaventura et al.
patent: 5352773 (1994-10-01), Kandler et al.
patent: 5386014 (1995-01-01), Nho et al.
patent: 5407428 (1995-04-01), Segall et al.
patent: 5438041 (1995-08-01), Zheng et al.
patent: 5439591 (1995-08-01), Pliura et al.
patent: 5449759 (1995-09-01), Hoffman et al.
patent: 5451205 (1995-09-01), Roth et al.
patent: 5464814 (1995-11-01), Sehgal et al.
patent: 5478805 (1995-12-01), Shorr et al.
patent: 5478806 (1995-12-01), Nho
patent: 5480866 (1996-01-01), Bonaventura et al.
patent: 5510464 (1996-04-01), Przybelski
patent: 5525630 (1996-06-01), Hoffman
patent: 5532352 (1996-07-01), Pliura et al.
patent: 5545328 (1996-08-01), Pliura et al.
patent: 5545727 (1996-08-01), Hoffman et al.
patent: 5554638 (1996-09-01), Dewhirst et al.
patent: 5563254 (1996-10-01), Hoffman et al.
patent: 5571801 (1996-11-01), Segall et al.
patent: 5574019 (1996-11-01), Segall et al.
patent: 5578564 (1996-11-01), Chivers et al.
patent: 5585484 (1996-12-01), Acharya et al.
patent: 5591710 (1997-01-01), Hsia
patent: 5595723 (1997-01-01), Quay
patent: 5599907 (1997-02-01), Anderson et al.
patent: 5612310 (1997-03-01), Dewhirst et al.
patent: 5613944 (1997-03-01), Segall et al.
patent: 5614490 (1997-03-01), Przybelski
patent: 5618919 (1997-04-01), Rausch et al.
patent: 5628930 (1997-05-01), Weers et al.
patent: 5631219 (1997-05-01), Rosenthal et al.
patent: 5635538 (1997-06-01), Weers et al.
patent: 5635539 (1997-06-01), Clark et al.
patent: 5650388 (1997-07-01), Shorr et al.
patent: 5661124 (1997-08-01), Hoffman et al.
patent: 5814601 (1998-09-01), Winslow et al.
patent: 5985825 (1999-11-01), Winslow et al.
patent: 6054427 (2000-04-01), Winslow
patent: 6269679 (2001-08-01), McCarthy et al.
patent: 6432918 (2002-08-01), Winslow
patent: 6500930 (2002-12-01), Adamson
patent: 6844317 (2005-01-01), Winslow et al.
patent: 6974795 (2005-12-01), Winslow et al.
patent: 2004/0072729 (2004-04-01), Kwang et al.
patent: 2430898 (1976-01-01), None
patent: 0340908 (1989-08-01), None
patent: 0361719 (1990-04-01), None
patent: 0478048 (1992-04-01), None
patent: 02124445 (1990-05-01), None
patent: WO 87/07832 (1987-12-01), None
patent: WO 90/13309 (1990-11-01), None
patent: WO 91/07190 (1991-05-01), None
patent: WO 9837909 (1998-09-01), None
Bouwer et al., “Diffusion Coefficients of Oxygen and Hemoglobin Measured by Facilitated Oxygen Diffusion Through Hemoglobin Solutions”,Biochim et Biophys Acta, 1338:127-136 (1997).
Chien, “Rheology in the Microcirculation in Normal and Low Flow States”,Advances in Shock Research80:71-80 (1992).
Frank et al., “A Finite-Element Model of Oxygen Diffusion in the Pulmonary Capillaries”,J. Appl. Physiol. 2036-2044 (1997).
Frazier, O.H., “Myocardial Revascularization with Laser—Preliminary Findings”,Circulation1995:92 (Supp. II;II-58-II-65).
Hellums et al., “Simulation of Intraluminal Gas Transport Processes in the Microcirculation”,Annals of Biomed Engineering24:1-24 (1996).
Intaglietta et al., “Microvascular and Tissue Oxygen Distribution”,Cardiovascular Research32:632-643 (1996).
Intaglietta, “Whiaker Lecture 1996: Microcirculation, Biomedical Engineering, and Artificial Blood”,Ann. Biomed. Engineer25:593-603 (1997).
Juszczak et al. “UV Resonance Raman Study of β93-Modified Hemoglobin A: Chemical Modifier-Specific Effects and Added Influences of Attached Poly(ethylene glycol) Chains”,Biochemistry41:376-385 (2002).
Kerger et al., “Systemic and Subcutaneous Microvascular Oxygen Tension in Conscious Syrian Golden Hamsters”,Am. J. Physiol. 267 (Heart Circ. Physiol. 37):H802-810 (1995).
Kim et al., “Oxygen Tension Regulates the Nitric Oxide Pathway”,J. Clin. Invest. 91:437-442 (1993).
Mirhashemi et al., “Model Analysis of the Enhancement of Tissue Oxygenation by Hemodilution Due To Increased Microvascular Flow Velocity”,Microvasc. Res. 34:290-301 (1987).
Mirhashemi et al., “Effects of Hemodilution On Skin Microcirculation”,Am. J. Physiol. 254:H411-H416 (1988).
Nishide et al., “Facilitated Oxygen Transport with Modified and Encapsulated Hemoglobins Across Non-Flowing Solution Membrane”,Art. Cells. Blood Su.b. and Immo.b Biotech., 25(4):335-346 (1997).
“Oxygen Diffuses from Arterioles to Capillaries”,NIPS224 (1990).
Papenfuss et al., “A Transparent Access Chamber for the Rat Dorsal Skin Fold”,Microvasc. Res. 18:311-318(1979).
Popel, Invited Editorial on “A Finite-Element Model of Oxygen Diffusion in the Pulmonary Capillaries”,J. Appl. Physiol.: 1717-1718 (1997).
Prouchayret et al., “A Potential Blood Substitute From Carboxyl Dextran and Oxyhemoglobin, I. Preparation, Purification, and Characterization”,Biomat. Art. Cells&lmmob. Biotech. 20:319-322 (1992).
Reinhart et al., “Rheologic Measurements on Small Samples with a New Capillary Viscosimeter”,J. Lab. Clin. Med. 104:921-931 (1984).
Stetter et al., “Influence
Vandegriff Kim D.
Winslow Robert M.
Audet Maury
Axford Laurie A.
Sangart, Inc.
The Nath Law Group
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