Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1994-01-12
1995-10-10
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424422, A61K 4730
Patent
active
054569176
ABSTRACT:
A method for making an implantable bioerodible material for the sustained release of a medicament and the material made from the method. The method comprises the formulation of a biomaterial polymeric carrier into particles of predetermined density and size. The particles are then are mixed with the desired medicament and extruded into the desired shape for implantation or reground to a predetermined size distribution for injection as a suspension. In an alternative embodiment, the particles of polymeric carrier are immersed in a solvent containing a medicament, and the pores of the particles are filled with medicament through alternate application and release of vacuum.
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Gresser Joseph D.
Trantolo Debra J.
Wise Donald L.
Cambridge Scientific, Inc.
Kulkosky Peter F.
Page Thurman K.
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